Chlorogenic acid health benefit

Chlorogenic acid is a dietary polyphenol found in many plants including green tea and green coffee bean. Chlorogenic acids are major secondary metabolites found in coffee seeds. Chlorogenic acid has a metabolite called m-coumaric acid.

Green Tea Extract, 100 mg
Diet Rx  FREE bottle formulated by Dr. Ray Sahelian, M.D.
Green Tea Extract offers a convenient way to get the benefits of green tea in a highly concentrated green tea pill form.  This green tea extract is standardized for bioflavonoid-like antioxidants known as polyphenols, particularly (-)-Epigallocatechin Gallate (EGCG). EGCG has been found in scientific studies to be a potent antioxidant. Green tea antioxidants are likely to become more popular with time.

Green Tea Supplement Facts
Calcium
Green Tea Extract Yielding 35 mg epigallocatechin gallate (EGCG)

Suggested Use: 1 green tea extract tablet a few times a week with breakfast or lunch. Take green tea extract pill in the morning or midday before or with a meal. Evening use may lead to mild insomnia.
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Chlorogenic acid for weight loss
The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people.
J Int Med Res. 2007 Nov-Dec. Thom E. ETC Research and Development, Oslo, Norway.
The results from a clinical study performed in 12 healthy volunteers with different coffee products containing glucose show that instant coffee enriched with chlorogenic acid induced a reduction in the absorption of glucose of 6.9% compared with control. No such effects were seen with normal or decaffeinated instant coffee. In a second, comparative, randomized, double-blind, 12-week study we investigated the effect on the body mass of 30 overweight people, compared with normal instant coffee. The average losses in mass in the chlorogenic acid enriched and normal instant coffee groups were 5.4 and 1.7 kg, respectively. We conclude that chlorogenic acid enriched instant coffee appears to have a significant effect on the absorption and utilization of glucose from the diet. This effect, if the coffee is used for an extended time, may result in reduced body mass and body fat when compared with the use of normal instant coffee.

Chlorogenic acid protects against radiation
Radioprotective effects of chlorogenic acid against mortality induced by g-irradiation in mice.
Methods Find Exp Clin Pharmacol. 2008 Jan-Feb. Hosseinimehr SJ, Zakaryaee V, Ahmadi A, Akhlaghpoor S. Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
The radioprotective effects of the naturally occurring compound chlorogenic acid have been investigated against mortality induced by gamma-irradiation in mice. Chlorogenic acid was administrated at single doses of 100, 200 and 400 mg/kg 1 or 24 h prior to lethal dose of gamma-irradiation (8.5 Gy). Chlorogenic acid exhibited concentration-dependent activity on 1,1-diphenyl-2-picrylhydrazyl free radical to show strong antioxidant activity. It appeared that chlorogenic acid with antioxidant activity reduced mortality induced by gamma-irradiation.

Chlorogenic acid raw herb and material suppliers
Chlorogenic acid is sold at 20 percent, 30 percent and 98 percent concentration.

Chemistry
Chlorogenic acid is the ester formed between certain trans cinnamic acid and (L)-quinic acid.

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